Why are Mesenchymal Stem Cells so interesting for industry and clinical research? The properties of Mesenchymal Stem Cells (MSCs) make them capable to be used for a broad application in research fields and the development of cell therapies. One topic is getting more important and looked
Preliminary report phase 1 clinical trial using a xeno-free & GMP compliant protocol with Human Platelet Lysate Madani et al. reported the short term safety of Placenta derived Mesenchymal Stem Cells (PLMSCs) transplanted in 4 children (Type 1 Diabetes Mellitus patients (T1DM)). The manufacturing of PLMSCs to the
"In vitro characterisation of 3D printed Platelet Lysate-based bioink for potential application in skin tissue engineering" In a lately published study Daikuara et al. developed an extrusion-based bio-ink consisting of Human Platelet Lysate (PL) and gelatin methacryloyl (GelMA). The bio-ink should be used for the 3D
World Earth Day 2021: Environmental Impact of HPL vs. FBS What do HPL and FBS have to do with the Earth Day 2021? The Earth Day raises awareness and educates people about a more sustainable living. For us, this means we educate about a more sustainable cell
ELAREM™ Prime is the worldwide first affordable cell culture supplement based on human platelets offering the same benefits as FBS – in an animal serum-free environment. What is ELAREM™ Prime? It is derived from reused transfusion-approved platelets. These platelets can no longer be used for blood transfusions,
A new publication from Kouroupis et al. published in CYTOTHERAPY in July 2020 found out that infrapatellar fat pad (IFP)-mesenchymal stem cells (MSCs) manufactured with human Platelet Lysate (hPL) show enhanced immunomodulatory properties. Findings have potential for a minimally invasive cell therapy for joint disease The authors even
The study performed with human Platelet Lysate (hPL) at the University of Miami showed an enhanced performance of manufactured IFP - MSCs under regulatory compliant conditions. The aim of the study was to proof the hypothesis: IFP-MSCs manufactured under these conditions do not need "ex-vivo priming
Human Platelet Lysate should seriously considered as the new standard "hPL has favorable properties in terms of ethics and scientific practice and should seriously be considered as a new standard cell culture medium substitute". HPL can replace FCS as a protein source This is only one of the
"We demonstrate that human platelet lysate (hPL) can replace hS in macrophage cultivation [
