Our customers’ research covers a large range of applications. To get a better picture and deeper understanding of the broad variety of Human Platelet Lysates’ usage we share some comments from our customers.
Our ELAREM™ Human Platelet Lysates are used as FBS replacement in 2D or 3D cell culture, organ-on-a-chip technologies or tissue engineering.
“Since 2019, we have initiated many musculoskeletal bioengineering projects using organ-on-a-chip and organoid technologies that aim to be animal-free. ELAREM™ as serum surrogate is ideally suited to provide primary human cells an animal-free environment to proliferate without any performance losses. My research group supports the use of serum substitutes such as ELAREM™ and we won’t ever go back to conventional FBS-based in vitro cultures. On a personal note, I hope to make an important contribution to the creation of disease and tissue models that are 100% animal-free for a more sustainable and moral approach to musculoskeletal disease modelling.”
Dr. Mario Rothbauer
Research Group Leader of the Orthopedic Microsystems Unit, Karl Chiari Lab for Orthopeadic Biology, Department of Orthopedics and Trauma Surgery, Medical University of Vienna
“The research field of tissue engineering (TE) gains great significance in regenerative therapeutic options of lost tissue functions. With regard to the subsequent clinical application and in order to increase the harmlessness of TE products, FBS supplementation of in vitro cell culture should be replaced by an alternative of human source. We have had great experience with the Human Platelet Lysate from PL BioScience.”
Prof. Dr. Dorothea Alexander-Friedrich
Research Laboratory Head, Clinic and Policlinic for Dental,
Oral and Maxillo-facial Surgery, University Hospital Tübingen
“We use ELAREM™ Perform for the cultivation of MSCs and are very satisfied, since the Human Platelet Lysate product serves as stable serum replacement in our media and the ‘performance’ is even superior to FCS or human Serum (e.g. with regard to promotion of cell growth).”
Prof. Dr. Cornelia Kasper
Dr.rer.nat. Dominik Egger
Biotechnology Institute for Cell and Tissue Culture Technologies, boku – University of Natural Resources and Life Sciences Vienna
“ELAREM™ Perform shows superiority compared to traditional FBS-based media not only in enhancing MSCs’ growth kinetic, phenotypic, molecular and secretory profiles in vitro, but most importantly in the actual functionality of ELAREM™ Perform-expanded MSCs to control pain and inflammation upon implantation in vivo. Collectively, HPL expansion of MSCs in vitro reinforce their paracrine-derived immunomodulatory/trophic (‘medicinal’) activities, streamlining manufacturing protocols for effective in vivo therapeutics.”
Dr. Diego Correa
Dr. Dimitrios Kouroupis
Miller School of Medicine, Diabetes Research Institute & Cell Transplant Center, University of Miami
“ELAREM™ Matrix is a flexibly applicable matrix in the form of a hydrogel, serving as a carrier structure, yet as a nutrient supplier for the cells. We are using ELAREM™ Matrix for the 3D cultivation and isolation of MSCs.”
Prof. Dr. Cornelia Kasper
Dr.rer.nat. Dominik Egger
Biotechnology Institute for Cell and Tissue Culture Technologies, boku – University of Natural Resources and Life Sciences Vienna
“HPL , a low cost rich source of growth factors, is a promising biomaterial constituent for formulating bioactive bioinks that will be utilised for fabrication of 3D cell-laden or cell-free structures in a range of applications in tissue engineering and regenerative medicine. Our work to date has demonstrated its potential in skin tissue engineering, with more work and collaboration to be undertaken in other areas of tissue engineering in the global research community, the benefits of HPL will be more broadly and increasingly appreciated.”
Dr. Zhilian Yue
School of Chemistry & Molecular Bioscience, Faculty of Science, Medicine and Health (SMAH), University of Wollongong
“ELAREM™ Perform has been used in our laboratory since 2017 to successfully cultivate and expand MSCs for in vitro as well as in vivo experiments to achieve potential tissue regeneration”
Univ. Prof. Dr. Gundula Schulze-Tanzil
Dr.rer.nat. Clemens Gögele
Paracelsus Medical University – Institute of Anatomy and Cell Biology
We work with a Quality Management System to safeguard work processes and procedures. Our Quality Management System provides a framework for measuring and improving our performance.
We are committed to offering and manufacturing safe products for research and GMP conform uses. To ensure our high quality, we monitor our suppliers, measure quality objectives, carry out regular audits of our internal processes, provide training for our employees. Our internal procedures are reviewed regularly.
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Technical Account Manager
Philipp is your contact person if you have questions about our products, prices and supply.
Silke is your contact person if you have technical questions about our products and their handling.
Business Development Manager
Franziska is your contact person if you have a question about current developments in the market. She is the connection to regulatory and scientific know-how.
